ABSTRACT
<p><b>OBJECTIVE</b>To understand and analyze the infection situation of Helicobacter pylori (H. pylori).</p><p><b>METHODS</b>Extensively reviewing Chinese literature collecting the related with electronic documents in combination with manual retrieve and using Meta-analysis to do a quantitative analysis.</p><p><b>RESULTS</b>Slight difference in the infection rate of H. pylori between men and women (95% CI: 0.0579-0.0963) was noticed. The infection rate of H. pylori in children whose parent was positive with infection of this bacteria was higher than that of children whose parent was negative (95% CI: 0.3378-0.5042).</p><p><b>CONCLUSION</b>The infection rate of H. pylori showed gender difference with nature of family aggregation. Epidemiological studies of H. pylori was comprehensive and involved many aspects. Further investigation needs to be focused on infection rate and other risk factors.</p>